Choosing the right flea and tick treatment for your dog can be confusing, especially when popular options like NexGard, Bravecto, and Seresto all claim effective protection. Each product works differently, offers varying durations of coverage, and suits different dog lifestyles. Understanding these differences is essential to making a safe and informed decision.
In this detailed comparison, we break down NexGard vs Bravecto vs Seresto based on effectiveness, duration, ease of use, safety considerations, and which type of dog each product is best suited for.
NexGard vs Bravecto vs Seresto
NexGard for Dogs
NexGard is a monthly oral chew that kills fleas and ticks after they bite your dog. It is flavored to improve acceptance and begins working within hours of administration.
Key highlights:
- Monthly dosing
- Effective against fleas and multiple tick species
- Suitable for dogs from 8 weeks of age (meeting weight requirements)
- Requires a prescription
Bravecto for Dogs
Bravecto is an oral chew that provides up to 12 weeks of protection against fleas and ticks, making it a longer-lasting option compared to monthly treatments.
Key highlights:
- One dose lasts up to 3 months
- Convenient for owners who may miss monthly doses
- Prescription required
- Available in chewable and topical forms (varies by region)
Seresto Collar for Dogs
Seresto is a long-acting flea and tick collar that releases active ingredients slowly over time and provides protection for up to 8 months.
Key highlights:
- No oral ingestion
- No monthly dosing required
- Continuous protection
- Water-resistant
NexGard vs Bravecto vs Seresto – Comparison Chart
Here’s a detailed comparison of NexGard Chews, Bravecto Chews and Seresto Flea and Tick Collar:

Effectiveness Against Fleas and Ticks
All three products are effective when used correctly. Oral treatments like NexGard and Bravecto start working after the parasite bites the dog, while Seresto works through contact before biting occurs. Dogs in high-tick areas may benefit from faster-acting oral options, whereas dogs with consistent exposure may benefit from continuous collar-based protection.
Safety and Side Effects
Most dogs tolerate these treatments well. However, some dogs may experience mild side effects such as vomiting, diarrhea, or lethargy. Oral isoxazoline-based products (NexGard and Bravecto) carry warnings for dogs with a history of neurological conditions, including seizures. Seresto may cause local skin irritation in sensitive dogs.
Always consult a veterinarian before starting or switching flea and tick treatments.
Which Product Is Best for Your Dog?
- Choose NexGard if you prefer a simple monthly routine and your dog accepts chewables easily.
- Choose Bravecto if you want longer protection with fewer doses per year.
- Choose Seresto if your dog cannot take oral medications or if you want extended, hands-free protection.
Lifestyle, age, health history, and parasite exposure should guide the final choice.
Frequently Asked Questions (FAQs)
What is the main difference between NexGard, Bravecto, and Seresto?
The main difference lies in how they are administered and how long they last. NexGard is monthly, Bravecto lasts up to 12 weeks, and Seresto provides up to 8 months of protection.
Which lasts longer: NexGard, Bravecto, or Seresto?
Seresto lasts the longest (up to 8 months), followed by Bravecto (up to 3 months), while NexGard requires monthly dosing.
Is Bravecto better than NexGard?
Bravecto may be more convenient for pet parents who prefer fewer doses, while NexGard suits those comfortable with monthly administration. Effectiveness is comparable when used correctly.
Is Seresto safer than oral flea treatments?
Seresto avoids oral ingestion, which may benefit dogs sensitive to oral medications. However, skin reactions can occur in some dogs. Veterinary guidance is recommended.
Do these products protect against heartworms?
No. NexGard, Bravecto, and Seresto do not prevent heartworm disease. Separate heartworm prevention is required.
Can puppies use NexGard, Bravecto, or Seresto?
These products are approved for puppies from a certain age and weight. Always check label instructions and consult a veterinarian.
Final Thoughts
There is no one-size-fits-all answer when comparing NexGard vs Bravecto vs Seresto. Each product offers proven flea and tick protection but serves different needs. By considering your dog’s lifestyle, health history, and your ability to maintain dosing schedules, you can confidently choose the option that keeps your dog protected year-round.
For dogs living in high-risk parasite areas, consistent prevention combined with regular grooming and environmental control offers the best results.prices from DiscountPetCare. Check out our online store to enjoy unbeatable offers on a range of pet treatments from the comfort of your home.
